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Motility of the left colon in children and adolescents with functional constpation; a retrospective comparison between solid‐state and water‐perfused colonic manometry
Author(s) -
Koppen I. J. N.,
Wiklendt L.,
Yacob D.,
Di Lorenzo C.,
Benninga M. A.,
Dinning P. G.
Publication year - 2018
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/nmo.13401
Subject(s) - medicine , catheter , high resolution manometry , meal , gastroenterology , constipation , retrospective cohort study , migrating motor complex , postprandial , barium meal , surgery , small intestine , esophagus , insulin , achalasia
Background Using water‐perfused ( WP ) high‐resolution manometry, we recently demonstrated that children with functional constipation ( FC ) lacked the postprandial increase in distal colonic cyclic motor patterns that was observed in healthy adults. Our aim was to determine if similar results could be detected using a solid‐state ( SS ) manometry catheter. Methods We performed a retrospective analysis of 19 children with FC (median age 11.1 years, 58% male) who underwent colonic manometry with a SS catheter (36 sensors, 3 cm apart). Data were compared with previously published data using a WP catheter (36 sensors, 1.5 cm apart) recorded from 18 children with FC (median age 15 years; 28% male). Key Results The cyclic motor patterns recorded by the SS catheter did not differ from those previously recorded by the WP catheter. There was no detected increase in this activity in response to the meal in either group. Long‐single motor patterns were recorded in most patients (n = 16, 84%) with the SS catheter. The number of these events did not differ from the WP recordings. In the SS data, HAPC s were observed in 4 children prior to the meal, in 5 after the meal. This did not differ significantly from the WP data. Conclusions & Inferences These data recorded by SS manometry did not differ from WP manometry data. Regardless of the catheter used, both studies revealed an abnormal colonic response to a meal, indicating a pathology which is not related to the catheter used to record these data.

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