Premium
Cortical visual areas process intestinal information during slow‐wave sleep
Author(s) -
Pigarev I. N.,
Bagaev V. A.,
Levichkina E. V.,
Fedorov G. O.,
Busigina I. I.
Publication year - 2013
Publication title -
neurogastroenterology and motility
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.489
H-Index - 105
eISSN - 1365-2982
pISSN - 1350-1925
DOI - 10.1111/nmo.12052
Subject(s) - sleep (system call) , neuroscience , peristalsis , duodenum , stimulation , proprioception , electroencephalography , cortex (anatomy) , electrophysiology , psychology , cerebral cortex , visual cortex , cats , neuroscience of sleep , slow wave sleep , anatomy , biology , medicine , computer science , operating system
Background Previously we have shown that, during sleep, electrical and magnetic stimulation of areas of the stomach and small intestine evoked neuronal and EEG responses in various cortical areas. In this study we wanted to correlate natural myoelectrical activity of the duodenum with cortical neuronal activity, and to investigate whether there is a causal link between them during periods of slow‐wave sleep. Methods We have recorded the myoelectrical activity from the wall of the duodenum and activity of single neurons from three cortical visual areas in naturally sleeping cats and investigated causal interrelationship between these structures during slow‐wave sleep. Key Results About 30% of the cortical neurons studied changed their firing rate dependent on the phases of the peristaltic cycle and demonstrated selectivity to particular pattern of duodenal myoelectrical activity during slow‐wave sleep. This interrelationship was never seen when awake. Conclusions & Inferences This observation supports the hypothesis that, during sleep, the cerebral cortex switches from processing of exteroceptive and proprioceptive information to processing of interoceptive information.