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Intracranial neuromuscular choristoma: Report of a case with literature review
Author(s) -
Coli Antonella,
Novello Mariangela,
Tamburrini Gianpiero,
Antonelli Manila,
Giangaspero Felice,
Lauriola Libero
Publication year - 2017
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1111/neup.12368
Subject(s) - choristoma , anatomy , cranial nerves , medicine , hamartoma , lesion , cerebellopontine angle , pathology , magnetic resonance imaging , radiology
Neuromuscular choristoma (NMC), also called neuromuscular hamartoma or nerve rhabdomyoma, is a rare lesion of the spinal and cranial nerves composed of skeletal muscle intimately associated with nerve fibers. Its origin has not been precisely clarified and a malformative event, resulting from aberrant differentiation or a true neoplastic growth, have been proposed by authors. We hereby present a cerebellopontine angle NMC enlarging the eighth cranial nerve in a 3‐year‐old child, that histologically appeared composed of a large amount of striated muscle mixed with nerve fibers. We also provide a review of the intracranial NMC cases reported in the literature and an analysis of proposed hypotheses to explain the presence of muscle cells in nerve trunks.