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Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo
Author(s) -
Higgins Gavin C.,
Nguyen TuongVi,
Ramm Georg,
Coughlan Melinda T.
Publication year - 2018
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.13251
Subject(s) - autophagy , ex vivo , flux (metallurgy) , medicine , in vivo , renal cortex , circumstantial evidence , microbiology and biotechnology , kidney , neuroscience , biology , materials science , biochemistry , genetics , metallurgy , apoptosis , political science , law
Summary at a Glance Autophagy is an important mechanism that maintains cell function. Alterations in autophagy occur in many renal diseases. This Methods in Renal Research article describes a new ex vivo approach to measure autophagic flux in the renal cortex. Will provide new insights into how autophagy is modified in kidney disease.