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Survival of patients with cancer starting chronic dialysis: Data from kidney and cancer registries in lower Normandy
Author(s) -
Béchade Clémence,
Dejardin Olivier,
Bara Simona,
Bouvier Véronique,
Guizard AnneValérie,
De Mil Rémy,
Troussard Xavier,
Launoy Guy,
Lobbedez Thierry
Publication year - 2018
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.13091
Subject(s) - medicine , dialysis , cancer , kidney disease , confidence interval , malignancy , kidney cancer , proportional hazards model , cancer registry , surgery
Aim Cancer and chronic kidney disease are known to be associated. The way in which a history of cancer can influence outcome in dialysis is not well described. This work aimed to evaluate survival of cancer patients starting chronic dialysis after their diagnosis of cancer. Methods We merged data from cancer registries and a dialysis registry, and explored patients' charts. Results Between January 2001 and December 2008, 74 patients with incident cancer in the two‐counties‐study‐area (Calvados and Manche) started chronic dialysis after their diagnosis of cancer. Survival of these incident dialysis patients with a previous diagnosis of cancer was respectively 80.9% (confidence interval 69.9; 88.2) and 68.3% (confidence interval 56.3%; 77.7%) at 1 and 2 years. Only 29 of the 74 patients (39.2%) were still alive at the end of the observation period; median participation time was 2.8 years (1 st and 3 rd quartiles: 1.3–4.4). Survival of patients with cancer was not different to that of non‐cancer dialysis patients matched for age and sex, except in patients with haematological malignancies who had a poorer outcome. In a multivariate stratified Cox model, the history of cancer before dialysis start was not associated with death, after adjustment on diabetes. Conclusion In our study, survival in dialysis was not different among patients with a history of cancer compared to matched patients without malignancy. We can hypothesize that only some selected patients with cancer have access to dialysis. Studies in ESRD patients with cancer should be performed to evaluate access to dialysis in that population.