Premium
Is there a role or target value for nutritional vitamin D in chronic kidney disease?
Author(s) -
Lim Wai H,
Duncan Emma L
Publication year - 2017
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.13027
Subject(s) - medicine , kidney disease , vitamin d and neurology , vitamin d deficiency , population , dialysis , disease , bone health , parathyroid hormone , vitamin , physiology , metabolic bone disease , endocrinology , intensive care medicine , osteoporosis , calcium , environmental health , bone mineral
Vitamin D is important for bone health in the general population but the value of vitamin D supplementation, and the role of 25‐hydroxyvitamin D independently of 1,25‐dihydroxyvitmain D, in individuals with chronic kidney disease (CKD), particularly in those who require dialysis, remains uncertain. Supplementation may improve some biochemical parameters, such as reducing PTH levels in patients to CKD‐stage 4 who have vitamin D deficiency; but it remains to be established whether the role of nutritional vitamin D in maintaining bone health in the general population can be extrapolated to the CKD population. There is currently insufficient evidence to recommend conclusively that nutritional vitamin D supplementation should be prescribed to individuals with CKD who have 25‐hydroxyvitamin D deficiency, either for skeletal or non‐skeletal health outcomes.