Premium
Nationwide epidemiology and prognosis of dialysis‐requiring acute kidney injury (NEP‐AKI‐D) study: Design and methods
Author(s) -
Shiao ChihChung,
Wu PeiChen,
Wu VinCent,
Lin JuiHsiang,
Pan HengChih,
Yang YaFei,
Lai TaiShuan,
Huang TaoMin,
Wu CheHsiung,
Yang WeiShun,
Wu ChihJen,
Kao ChihChin,
Sun ChiaoYin,
Huang ChunTe,
Lee KuoHua,
Lin ChanYu,
Chen TeChuan,
Hu FuChang,
Liou HungHsiang,
Lu KuoCheng,
Chien KuoLiong,
Wang JianJhong,
Kan WeiChih,
Kuo FengChi,
Lin Hugo YouHsien,
Chen ChengMin,
You Zihong,
Tsai JenPi,
Weng ChihJen,
Chen HungYuan,
Chang ChaoFu,
Hsu WenDing,
Wu MaiSzu,
Huang ChiuChing,
Wu KwanDun
Publication year - 2016
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.12670
Subject(s) - medicine , acute kidney injury , dialysis , epidemiology , intensive care medicine , incidence (geometry) , emergency medicine , kidney disease , mortality rate , intensive care unit , physics , optics
Aim Acute kidney injury (AKI) carries an increasing incidence rate worldwide and increases the risk of developing end‐stage renal disease (ESRD) as well as the medical expenses during the post‐AKI course. The Taiwan Consortium for Acute Kidney Injury and Renal Diseases (CAKs) has thus launched a nationwide epidemiology and prognosis of dialysis‐requiring acute kidney injury (NEP‐AKI‐D) study, which prospectively enrols critically ill patients with AKI. Through thoroughly evaluating the risk and prognostic factors of AKI, we hope to lower the incidence of AKI and ESRD from the perspective of AKI‐ESRD interaction. Methods The CAKs includes 30 hospitals which distribute widely through the four geographical regions (north, middle, south, and east) of Taiwan, and have a 1:1 ratio of medical centres to regional hospitals in each region. The NEP‐AKI‐D study enrols intensive care unit‐based AKI patients who receive dialysis in the four seasonal sampled months (October 2014, along with January, April, and July 2015) in the included hospitals. The collected data include demographic information, pertaining laboratory results, dialysis settings and patient outcomes. The data are uploaded in a centre website and will be audited by on‐site principal investigators, computer logic gates, and the CAKs staffs. The outcomes of interest are in‐hospital mortality, dialysis‐dependency and readmission rate within 90 days after discharge. Conclusion The NEP‐AKI‐D study enrols a large number of representative AKI patients throughout Taiwan. The results of the current study are expected to provide more insight into the risk and prognostic factors of AKI and further attenuated further chronic kidney disease transition.