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Mortality in hospitalized chronic kidney disease patients starting unplanned urgent haemodialysis
Author(s) -
Panocchia Nicola,
Tazza Luigi,
Di Stasio Enrico,
Liberatori Massimo,
Vulpio Carlo,
Giungi Stefania,
Lucani Giovanna,
Antocicco Manuela,
Bossola Maurizio
Publication year - 2016
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.12561
Subject(s) - medicine , kidney disease , dialysis , renal function , logistic regression , mortality rate , observational study , hemodialysis , coma (optics) , optics , physics
Abstract Aim Data on the outcome of chronic kidney disease ( CKD ) patients who are hospitalized and start unplanned urgent haemodialysis ( HD ) are lacking. This prospective, longitudinal, observational study aimed to define the hospital mortality rate and associated factors in CKD patients who start unplanned urgent HD . Methods Between J anuary 2003 and D ecember 2009, all patients with CKD who were hospitalized, diagnosed with ESRD and started unplanned urgent haemodialysis at H aemodialysis S ervice of the C atholic U niversity of R ome, I taly were recruited. Exclusion criteria were: acute renal failure, prior history of dialysis, multiple organ failure, coma, and dementia. Hospital mortality rate was the primary outcome. Results Three and hundred sixteen patients were studied: 99 died after 19.5 ± 27.3 days and 217 survived until discharge. Of these, 154 were prescribed chronic HD and 63 restored renal function. Patients who died were significantly older and had a higher C harlson C omorbidity I ndex score. The mortality rates were 51.1% in patients with 81–90 years, 37.8% with 71–80 years, 34.1% with 61–70 years and 13.9% with age ≤60 years. Logistic regression analysis showed that age only was an independent risk factor for all‐cause mortality. Conclusions In CKD patients who need hospitalization and start unplanned urgent haemodialysis the mortality is very high and significantly related to age.