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Mesenchymal stem cells and transplant tolerance
Author(s) -
Vanikar Aruna V,
Trivedi Hargovind L,
Kumar Ashutosh,
Gopal Saroj Chooramani,
Kute Vivek B
Publication year - 2014
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.12258
Subject(s) - medicine , mesenchymal stem cell , stem cell , microbiology and biotechnology , pathology , biology
Different strategies are being tried to induce transplant tolerance in clinical settings; however, none of them are both safe and effective. Mesenchymal stem cells have been found to be potent immunomodulators and immunosuppressants. We discuss in this review different sources of mesenchymal stem cells and the potent role of adipose tissue‐derived mesenchymal stem cells in induction of transplant tolerance including when to use them and how to use them for achieving the U topian dream of transplant tolerance.