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Obesity and its relation to chronic kidney disease: A population‐based, cross‐sectional study of a T hai army population and relatives
Author(s) -
Satirapoj Bancha,
Supasyndh Ouppatham,
Mayteedol Natee,
Punpanich Dollapas,
Chaiprasert Amnart,
Nata Naowanit,
Ruangkanchanasetr Prajej,
Kanjanakul Inseey,
Choovichian Panbubpa
Publication year - 2013
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.12023
Subject(s) - medicine , overweight , kidney disease , waist , obesity , renal function , body mass index , population , abdominal obesity , cross sectional study , logistic regression , gastroenterology , endocrinology , environmental health , pathology
Aim Obesity represents a significant problem in patients with cardiovascular disease and chronic kidney disease ( CKD ). The aim of the present study was to investigate the association between body mass index ( BMI ) and CKD in T hai individuals. Methods Participants underwent general health screening. Overweight, weight at risk, obese I and obese II were defined as having a BMI ≥23 kg/m 2 , 23–24.9 kg/m 2 , 25–29.9 kg/m 2 and ≥30 kg/m 2 , respectively. Waist circumference ≥ 90 cm for men and > 80 cm for women were represented by abdominal obesity. CKD was defined as a glomerular filtration rate ( GFR ) < 60 mL /min per 1.73 m 2 . An estimate of the GFR was obtained by the four‐variable M odification of D iet in R enal D isease ( MDRD ) equation. Results The study population had 12 348 males and 3009 females. The survey population had a 7.5% prevalence of CKD . There was also a significant graded relationship between the degrees of overweight with the prevalence of CKD . Mean BMI were 25.36 ± 3.29 kg/m 2 for CKD subjects and 24.04 ± 3.13 kg/m 2 for non‐ CKD subjects ( P < 0.001). Prevalence of overweight and abdominal obesity in the participants with CKD were found to be higher than in those without CKD (overweight, 77.6% vs. 61.6%, P < 0.001; abdominal obesity, 35.7% vs. 25.3%, P < 0.001). In a multivariate logistic regression analysis, weight at risk (adjusted odds ratio 1.29; 95% CI 1.07–1.54), obese I (adjusted odds ratio 1.58; 95% CI 1.33–1.87) and obese II (adjusted odds ratio 1.65; 95% CI 1.24–2.19) were associated with CKD . Conclusion Our data showed that overweight and obesity were associated with CKD in Thai members of the army population and their relatives undergoing a general health screening, independently of age, gender, blood pressure, serum lipid, uric acid and glucose levels.