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Complexity reduction of chromatin architecture in macula densa cells during mouse postnatal development
Author(s) -
Pantic Igor,
BastaJovanovic Gordana,
Starcevic Vesna,
Paunovic Jovana,
Suzic Slavica,
Kojic Zvezdana,
Pantic Senka
Publication year - 2013
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1111/nep.12003
Subject(s) - medicine , macula densa , reduction (mathematics) , microbiology and biotechnology , chromatin , genetics , biology , dna , renin–angiotensin system , blood pressure , geometry , mathematics
An observation study in mice suggesting that the chromatin of macula densa cells undergoes loss of structural complexity that is most pronounced immediately after birth and remains during the first month of postnatal life. The findings add to the knowledge about the changes that take place in the kidney during postnatal development function and tissue structural organization, which are linked to changes in physiological function.