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Cerebral blood flow increase in striatum by choreoathetosis: N ‐isopropyl‐ p ‐[ 123 I]iodoamphetamine single‐photon emission computed tomography findings
Author(s) -
Kikyo Hideyuki,
Yamamoto Masahiro,
Yamada Hitoshi
Publication year - 2014
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.95
Subject(s) - choreoathetosis , single photon emission computed tomography , medicine , cerebral blood flow , striatum , isopropyl , nuclear medicine , emission computed tomography , blood flow , computed tomography , anesthesia , positron emission tomography , radiology , dopamine , dystonia , chemistry , organic chemistry , psychiatry
A 75‐year‐old man presented choreoathetosis dominantly on his left side. Diffusion‐weighted imaging did not show abnormal intensities, whereas N ‐isopropyl‐ p ‐[ 123 I]iodoamphetamine single‐photon emission computed tomography showed a significant cerebral blood flow increase in the right striatum. The patient was treated with a D2‐blocker agent, and the choreoathetosis gradually decreased. The cerebral blood flow on the right striatum decreased by the following N ‐isopropyl‐ p ‐[ 123 I]iodoamphetamine single‐photon emission computed tomography. We discussed the mechanism of choreoathetosis from the perspective of the direct and indirect pathways in motor control.