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Post‐Influenza vaccine‐induced acute hemorrhagic leukoencephalitis treated with plasma exchange—A case report
Author(s) -
Koenig Zachary,
Prasad Apoorv,
Altaweel Laith,
Sriwastava Shitiz
Publication year - 2021
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12535
Subject(s) - medicine , acute disseminated encephalomyelitis , pons , magnetic resonance imaging , complication , vaccination , therapeutic plasma exchange , intracerebral hemorrhage , pediatrics , pathology , surgery , radiology , glasgow coma scale
Acute Hemorrhagic Leukoencephalitis (AHLE) is a rare but devastating and fatal form of Acute Disseminated Encephalomyelitis. Very rarely, this can be a complication of vaccination. There is currently no consensus on the optimal treatment strategy of AHLE. We present a rare case of AHLE after seasonal influenza vaccine promptly diagnosed with magnetic resonance imaging (MRI) brain, which showed significant areas of hemorrhage with vasogenic edema including involvement of the pons. The patient was aggressively treated with plasma exchange and corticosteroids and had a favorable outcome.