Premium
Neurosyphilis presenting as herpes simplex virus encephalitis
Author(s) -
Li FangZhou,
Tian Jun,
Zhang Yun,
Wu ZhiYing
Publication year - 2021
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12486
Subject(s) - medicine , neurosyphilis , encephalitis , herpes simplex virus , treponema , magnetic resonance imaging , cerebrospinal fluid , temporal lobe , lesion , brain biopsy , pathology , penicillin , virology , syphilis , virus , radiology , antibiotics , psychiatry , microbiology and biotechnology , human immunodeficiency virus (hiv) , biology , epilepsy
A 63‐year‐old woman was admitted to our hospital complaining of sudden slow response and irrelevant answer for three days. The brain magnetic resonance imaging revealed a left‐sided hyperintense lesion and moderate expansiveness involving the hippocampus, insular cortex, and temporal lobe, which mimicking herpes simplex virus encephalitis. Her cerebrospinal fluid examination disclosed the Treponema pallidum particle agglutination assay and rapid plasma regain test were both positive. A diagnosis of neurosyphilis was made, and the patient was benefited from penicillin therapy.