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Reliability and validity of Japanese version of Unified Multiple System Atrophy Rating Scale
Author(s) -
Chikada Ayaka,
Mitsui Jun,
Matsukawa Takashi,
Ishiura Hiroyuki,
Toda Tatsushi,
Ogata Katsuhisa,
Goto Jun,
Wenning Gregor K.,
Tsuji Shoji
Publication year - 2021
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12477
Subject(s) - cronbach's alpha , rating scale , rank correlation , medicine , spearman's rank correlation coefficient , kappa , reliability (semiconductor) , physical therapy , psychology , statistics , psychometrics , clinical psychology , mathematics , developmental psychology , power (physics) , physics , quantum mechanics , geometry
Background/Aim The Unified Multiple System Atrophy Rating Scale (UMSARS) has been broadly used to assess the progression of multiple system atrophy (MSA). In this study, we translated UMSARS into Japanese and tested the reliability and validity of the translated version for the assessment of Japanese patients with MSA. Method UMSARS was translated into Japanese. For the evaluation of the reliability of the translated version, 60 and 70 participants with MSA were assessed by two neurologists using the Japanese versions of UMSARS‐I and UMSARS‐II, respectively. For the validation, 70 participants with MSA were evaluated by one neurologist using the Japanese versions of UMSARS‐I and UMSARS‐II, and other scales. Cronbach's alpha coefficient, Cohen's kappa coefficient [κ (w)], and Spearman rank correlation were calculated. Results Cronbach's alpha coefficients of the Japanese versions of UMSARS‐I and UMSARS‐II were 0.87 and 0.90, respectively. The κ (w) values of UMSARS‐I and UMSARS‐II items were 0.61‐0.81 and 0.51‐0.86, respectively. The total UMSARS‐I score correlated well with the scores of Barthel Index, Schwab and England Activities of Daily Living Scale, Functional Independence Measure, and Movement Disorder Society‐Unified Parkinson's Disease Rating Scale (MDS‐UPDRS) part 2 (Spearman rank correlations, −0.75, −0.71, −0.82, and 0.81, respectively). The total UMSARS‐II score correlated well with the scores of International Cooperative Ataxia Rating Scale and MDS‐UPDRS part 3 (Spearman rank correlations, 0.85 and 0.86, respectively). Conclusions The Japanese version of UMSARS is reliable and valid for the assessment of the clinical severity of MSA in Japan.