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A unique case with positive anti‐myelin oligodendrocyte glycoprotein antibody presenting multiple brain lesions
Author(s) -
Matsumoto Namiko,
Sato Kota,
Hishikawa Nozomi,
Kawahara Yuko,
Takemoto Mami,
Ohta Yasuyuki,
Yamashita Toru,
Fujii Kentaro,
Kurozumi Kazuhiko,
Date Isao,
Takahashi Toshiyuki,
Abe Koji
Publication year - 2020
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12364
Subject(s) - medicine , myelin oligodendrocyte glycoprotein , pathology , lesion , oligodendrocyte , antibody , white matter , central nervous system , myelin , multiple sclerosis , brainstem , immunology , magnetic resonance imaging , radiology
The accurate diagnosis of anti‐myelin oligodendrocyte glycoprotein (MOG) antibody‐associated diseases is sometimes challenging due to its various central nervous system (CNS) lesions. Here, we report a 22‐year‐old man with positive anti‐MOG antibody presenting multiple brain lesions including a brainstem tumefactive demyelinating lesion (TDL), cortical edematous lesions, and a periventricular white matter lesion. These variety of lesions made the diagnosis challenging, especially because TDL is quite rare among MOG antibody‐associated disease patients. The present case suggests the importance to check anti‐MOG antibody for patients presenting atypical multiple CNS lesions.