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Phantom bedside intruder in Parkinson's disease
Author(s) -
Ting Simon Kang Seng,
Chen Celeste,
Hameed Shahul,
Ng Adeline,
Kandiah Nagaendran,
Prakash Kumar M,
Xie Wanying,
Lam Winnie WingChuen,
Sin Gwen Li,
Chan Ling Ling,
RosaNeto Pedro,
Gauthier Serge,
Ng Kok Pin
Publication year - 2019
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12258
Subject(s) - psychosis , medicine , supramarginal gyrus , parkinson's disease , neuroimaging , insula , superior temporal gyrus , audiology , neuroscience , disease , psychiatry , physical medicine and rehabilitation , psychology , radiology , functional magnetic resonance imaging
Psychosis is a known neuropsychiatric feature in Lewy body disease. While visual hallucination remained the most common form of psychosis, a minor proportion of patients suffer from multimodal psychosis in Parkinson's disease ( PD ). However, current research does not always specify whether multimodal psychosis is manifested in an independent, sequential, or concomitant manner. As such, studies addressing brain–behavior relationship of multimodal psychosis remain sparse. In this paper, we described a case of PD multimodal psychosis manifesting as a phantom bedside intruder, where the patient episodically “felt” the presence and “heard” the breathing sound of the “person” without visualizing him. [ 18 F]fluorodeoxyglucose‐positron emission tomography scan showed predominant hypometabolism in brain regions involving the bilateral insula, superior temporal gyrus, supramarginal gyrus, and anterior cingulate. The unusual multimodal phantom bedside intruder phenomenon observed in this case is likely a result of combinational dysfunction of bilateral temporal parietal lobes.