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Vogt–Koyanagi–Harada case accompanied by polyneuropathy
Author(s) -
Tsunoda Keiichiro,
Ohta Yasuyuki,
Tadokoro Koh,
Sasaki Ryo,
Takahashi Yoshiaki,
Sato Kota,
Nomura Emi,
Takemoto Mami,
Hishikawa Nozomi,
Yamashita Toru,
Kajita Ai,
Abe Koji
Publication year - 2018
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12213
Subject(s) - medicine , polyneuropathy , dermatology , skin biopsy , weakness , central nervous system , vasculitis , muscle biopsy , nervous system , biopsy , sural nerve , pathology , disease , surgery , psychiatry
Vogt–Koyanagi–Harada disease ( VKHD ) is a systemic autoimmune disease that targets melanocyte‐rich tissues such as eye, central nervous system, inner ear, and skin. Here, we report a case of VKHD accompanied by polyneuropathy. After VKHD was diagnosed, depending on the involvement of bilateral ocular, auditory, and central nervous systems, he expressed muscle weakness, pain, and numbness in bilateral lower extremities. Nerve conduction studies suggested sensorimotor polyneuropathy, while a skin, muscle, and nerve biopsy suggested vasculitis. Steroid therapy improved his symptoms. The present case might suggest a relationship between VKHD and polyneuropathy.