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Holmes’ tremor caused by coexisting Parkinson's disease in a case of spinocerebellar ataxia type 31
Author(s) -
Shimizu Kazutaka,
Hanajima Ritsuko,
Satou Sumito,
Shimizu Takahiro,
Watanabe Katsushige,
Kaneko Atsushi,
Iizuka Takahiro,
Nishiyama Kazutoshi
Publication year - 2017
Publication title -
neurology and clinical neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2049-4173
DOI - 10.1111/ncn3.12114
Subject(s) - medicine , thalamotomy , essential tremor , spinocerebellar ataxia , ataxia , parkinson's disease , resting tremor , dopaminergic , neuroscience , cerebellar ataxia , intention tremor , physical medicine and rehabilitation , disease , psychology , deep brain stimulation , pathology , psychiatry , dopamine
Holmes’ tremor is a low‐frequency resting and intention tremor. Here, we report a case of spinocerebellar ataxia type 31 with an unusual presentation of Holmes’ tremor. We traced it to the development of Parkinson's disease in the patient. L‐dopa was insufficient for tremor, but zonisamide and ventralis intermedius thalamotomy were effective. Both cerebellar and dopaminergic system damage are thus required to express Holmes’ tremor.