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Placental HIV transmission and vitamin D : Nutritional and immunological implications
Author(s) -
Fitchett J. R.
Publication year - 2013
Publication title -
nutrition bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.933
H-Index - 40
eISSN - 1467-3010
pISSN - 1471-9827
DOI - 10.1111/nbu.12061
Subject(s) - human immunodeficiency virus (hiv) , transmission (telecommunications) , vitamin , medicine , placenta , vitamin d and neurology , immunology , pregnancy , vitamin d deficiency , adverse effect , physiology , fetus , biology , electrical engineering , engineering , genetics
Summary Vitamin D is a well‐known immunomodulator. The relationship between vitamin D status and human immunodeficiency virus ( HIV ) infection has attracted attention in recent literature. Evidence suggests there may be increased prevalence of vitamin D deficiency in HIV ‐infected children compared with HIV sero‐negative counterparts. One study has linked increased mother‐to‐child transmission of HIV , child mortality and adverse perinatal outcomes to vitamin D deficiency. This article provides a brief introduction into the emerging information surrounding the role of vitamin D and the placenta on mother‐to‐child transmission of HIV .