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Microglial contribution to synaptic uptake in the prefrontal cortex in schizophrenia
Author(s) -
Tzioras M.,
Stevenson A. J.,
Boche D.,
SpiresJones T. L.
Publication year - 2021
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/nan.12660
Subject(s) - neuroscience , prefrontal cortex , schizophrenia (object oriented programming) , psychology , medicine , psychiatry , cognition
Microglia in human post‐mortem tissue in schizophrenia patients' brains engulf synaptic material, but not differently to age‐matched non‐neurological control brains. Also, schizophrenia brains display similar levels of microgliosis to control brains.