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Tau aggregates: where, when, why and what consequences?
Author(s) -
Frosch M. P.
Publication year - 2017
Publication title -
neuropathology and applied neurobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.538
H-Index - 95
eISSN - 1365-2990
pISSN - 0305-1846
DOI - 10.1111/nan.12400
Subject(s) - locus coeruleus , dorsal raphe nucleus , neuroscience , disease , dorsum , tau pathology , raphe nuclei , alzheimer's disease , medicine , nucleus , psychology , pathology , serotonergic , anatomy , serotonin , receptor
The significance of tau pathology in the locus coeruleus and dorsal raphe nucleus in Alzheimer's disease is considered, both in terms of our understanding of disease mechanisms, and also the implications for treatment strategies.