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Ergebnisse einer Kombinationsbehandlung mit Natamycin und Butylscopolamin bei intestinaler Candida ‐Besiedlung
Author(s) -
Gehring W.,
Späte W.,
Gehse M.,
Gloor M.,
Braun K. J.
Publication year - 1990
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.1990.33.3.140
Subject(s) - natamycin , feces , colonization , population , microbiology and biotechnology , fungus , medicine , biology , food science , botany , environmental health
Summary The findings described show that Candida species can be found in the feces of approximately half a population of non‐selected test persons and in the mouths of approximately a third. Intestinal Candida colonization was found in most of these persons after one feces examination, and in practically all of them after a second examination. 10 d of therapy with 400 mg natamycin per day in sugarcoated tablet form and 40 mg natamycin in the form of tablets for sucking produced a negative fungus test for the feces in only 20 % of the cases. Although a combination of this therapy with 3 x 10 mg butylscopolamine per day improved short‐term results significantly, the long‐term results were hardly influenced at all. Typifying results according to the Warnock method showed that we are dealing with recurrences in practically all cases and not with new infections. Minimal inhibition concentrations (MIC) of natamycin showed no marked changes as a consequence of the natamycin treatment.