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Fusarium onychomycoses in Switzerland—A mycological and histopathological study
Author(s) -
Rammlmair Anna,
Mühlethaler Konrad,
Haneke Eckart
Publication year - 2019
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12964
Subject(s) - trichophyton rubrum , dermatophyte , dermatology , nail (fastener) , itraconazole , terbinafine , medicine , griseofulvin , nail disease , antifungal , paronychia , materials science , metallurgy
Summary Onychomycoses in temperate climates are most commonly due to dermatophytes, particularly Trichophyton rubrum . Non‐dermatophyte nail infections are much less frequent, and their diagnosis requires a careful and repeated search for a potential dermatophyte that may have been overgrown in culture. A series of histological slides of suspected onychomycoses with uncommon fungal morphology prompted us to search for non‐dermatophytic moulds causing dermatophytosis‐like nail infections. Thirty cases were identified by culture as F solani , F oxysporum, F dimerum or F spp, and two more were only diagnosed histopathologically. None of these patients was immunocompromised. Treatment was mostly unsuccessful with terbinafine whereas itraconazole showed a moderately better treatment result; in all cases, a topical ciclopirox nail varnish in a hydroxychitosan base was added.