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Successful treatment of chromoblastomycosis of 10‐year duration due to Fonsecaea nubica
Author(s) -
He Liya,
Ma Jianchi,
Mei Xin,
Lu Sha,
Li Xiqing,
Xi Liyan
Publication year - 2018
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12732
Subject(s) - chromoblastomycosis , terbinafine , itraconazole , medicine , dermatology , surgery , pathology , antifungal
Summary We report a case of chromoblastomycosis due to the presence of large plaque and verrucous hyperplasia lesions on the left upper limb, with elbow abnormal activities, in a 56‐year‐old male. The diagnosis of chromoblastomycosis was based on gross and microscopic morphologies, histopathological examination and clinical manifestation. Molecular tools were applied to identifying the causative agent Fonsecaea nubica , which is rarely reported to be associated with chromoblastomycosis. The patient was initially treated orally with terbinafine (250 mg/day) and itraconazole (200 mg/day), subsequently patient received thermotherapy (45‐50°C, 3 h/day) for 1 month. The patient was successfully cured. A literature review was performed to assess general features, treatment and outcome of chromoblastomycosis due to F. nubica . All the 5 reviewed patients were male, over 30 years old and their lesions occurred after traumatic inoculation.