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A case of chromoblastomycosis by Fonsecaea nubica indicating a possible insect route of transmission
Author(s) -
Chen Yingdan,
Yin Songchao,
Li Meirong,
Chen Rongzhang,
Wei Ling,
Ma Han,
Deng Shuwen,
de Hoog Gert Sybren,
Lai Wei,
Lu Chun,
Feng Peiying
Publication year - 2016
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12523
Subject(s) - chromoblastomycosis , terbinafine , itraconazole , biology , flea , pathology , dermatology , medicine , antifungal , zoology
Summary A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42‐year‐old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10‐year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer ( ITS ). The patient showed marked clinical improvement after 3 months combination therapy with itraconazole and terbinafine. The possible mode of transmission of auricular chromoblastomycosis is discussed.