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First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient
Author(s) -
Tap Ratna Mohd,
Ho Betty Lee Sue,
Ramli Nur Yasmin,
Suppiah Jeyanthi,
Hashim Rohaidah,
Sabaratnam Parameswari,
Ginsapu Stephanie Jane,
Gowbei Annabel,
Razak Mohd Fuat Abd,
Sipiczki Matthias,
Ahmad Norazah
Publication year - 2016
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12509
Subject(s) - caspofungin , anidulafungin , voriconazole , fluconazole , internal transcribed spacer , microbiology and biotechnology , biology , polymerase chain reaction , micafungin , antifungal , medicine , ribosomal rna , gene , genetics
Summary Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C . wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name as UZ 1679/14, in which the identification was confirmed by a polymerase chain reaction‐sequencing of the internal transcribed spacer ( ITS ) and large subunit ( LSU ) regions of the rRNA gene. Antifungal susceptibility pattern showed that the isolate was sensitive to anidulafungin, caspofungin, fluconazole and voriconazole. The patient clinically improved after the antifungal treatment with caspofungin.