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Disseminated fusariosis by Fusarium proliferatum in a patient with aplastic anaemia receiving primary posaconazole prophylaxis – case report and review of the literature
Author(s) -
Ricna Dita,
Lengerova Martina,
Palackova Martina,
Hadrabova Marketa,
Kocmanova Iva,
Weinbergerova Barbora,
Pavlovsky Zdenek,
Volfova Pavlina,
Bouchnerova Jana,
Mayer Jiri,
Racil Zdenek
Publication year - 2016
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12421
Subject(s) - fusariosis , posaconazole , fusarium proliferatum , medicine , antifungal , dermatology , fusarium , immunology , biology , amphotericin b , horticulture
Summary Disseminated fusariosis is a life‐threatening, invasive, opportunistic infection in immunocompromised patients, especially those with haematological malignancies. The prognosis is poor because these fungi are resistant to many of the available antifungal agents. We present a case of disseminated fusariosis caused by Fusarium proliferatum in a patient with severe aplastic anaemia complicated by a secondary infection of Aspergillus flavus , with a fatal outcome. We also review the documented Fusarium infections in immunocompromised hosts.