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Pulmonary Cryptococcosis in HIV‐ sero‐negative patients: case series from India
Author(s) -
Chopra Shimpi,
Capoor Malini R.,
Mallik Rupali,
Gupta Sonal,
Ray Animesh,
Khanna Geetika,
Suri J. C.,
Bhattacharya D.,
Raghavan Samudrala
Publication year - 2015
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12313
Subject(s) - medicine , cryptococcosis , pregnancy , tuberculosis , diabetes mellitus , pulmonary tuberculosis , immunology , pediatrics , pathology , genetics , biology , endocrinology
Summary Pulmonary cryptococcosis is likely to be misdiagnosed due to relatively non‐specific clinical and radiological features. It is more frequently associated with immuno‐suppressed conditions especially acquired immuno‐deficiency syndrome ( AIDS ) and pulmonary tuberculosis ( PTB ). Four cases of pulmonary cryptococcosis were diagnosed over a period of eleven years. All patients in this case series were human immune‐deficiency virus ( HIV )‐negative. The predisposing factors in these patients were diabetes mellitus ( DM ), acute lymphoblastic leukaemia ( ALL ), post‐partum and pregnancy in one each of the patients. Relapse was seen in two cases. All the patients survived due to strict follow‐up. Pulmonary cryptococcosis is common in non‐ AIDS patients and it warrants rapid diagnosis, treatment and follow‐up to prevent relapse.