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First case of disseminated cryptococcosis in a Gorilla gorilla
Author(s) -
Mischnik Alexander,
Stockklausner Julia,
Hohneder Nicole,
Jensen Henrik E.,
Zimmermann Stefan,
Reuss David E.,
Rickerts Volker,
Tintelnot Kathrin,
Stockklausner Clemens
Publication year - 2014
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12215
Subject(s) - cryptococcus neoformans , cryptococcosis , lethargy , immunosuppression , gorilla , cryptococcus , biology , histopathology , immunology , immune system , virology , lung , pathology , microbiology and biotechnology , medicine , paleontology
Summary In humans, Cryptococcus mainly infects individuals with HIV infection or other types of immunosuppression. Here, we report the first case of disseminated cryptococcosis in a simian immunodeficiency virus‐negative 27‐year‐old female G orilla gorilla presenting with lethargy, progressive weight loss and productive cough. The diagnosis was confirmed by positive lung biopsy culture, serum cryptococcal antigen, and cerebral histopathology demonstrating encapsulated yeasts. Molecular characterisation of lung culture isolate yielded C ryptococcus neoformans var. grubii . An immune‐deficiency could not be demonstrated.