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Primary cutaneous cryptococcosis in an immunocompetent patient due to Cryptococcus gattii molecular type VGI in Brazil: a case report and review of literature
Author(s) -
Nascimento Erika,
Bonifácio da Silva Maria Emília Nadaletto,
Martinez Roberto,
Zeska Kress Marcia Regina
Publication year - 2014
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12176
Subject(s) - cryptococcus gattii , cryptococcosis , cryptococcus neoformans , cryptococcus , mating type , biology , fluconazole , microbiology and biotechnology , dermatology , antifungal , medicine , biochemistry , gene
Summary Primary Cutaneous Cryptococcosis is an uncommon infection caused by the yeast Cryptococcus neoformans and C. gattii . Few case reports are available in the literature describing in detail primary cutaneous cryptococcosis due to C. gattii in immunocompetent patients. Herein, we present a case of a 68‐year‐old immunocompetent male patient with erythematous nodular lesions on the right forearm due to C. gattii mating‐type α and molecular type VGI . The virulence factors test was performed for capsule diameter, melanin production and phospholipase activity. In vitro fluconazole testing showed the sensitivity profile of this clinical isolate. In addition, a review of the literature on this subject was carried out and verified that this is the first reported case of VGI in the south‐east region of Brazil.