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Fungal diseases mimicking primary lung cancer: radiologic–pathologic correlation
Author(s) -
Gazzoni Fernando F.,
Severo Luiz Carlos,
Marchiori Edson,
Irion Klaus L.,
Guimarães Marcos D.,
Godoy Myrna C.,
Sartori Ana P. G.,
Hochhegger Bruno
Publication year - 2014
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12150
Subject(s) - histoplasmosis , paracoccidioidomycosis , medicine , blastomycosis , cryptococcosis , pathology , aspergillosis , lung cancer , mucormycosis , lung , etiology , mycosis , cancer , biopsy , dermatology , radiology , immunology
Summary A variety of fungal pulmonary infections can produce radiologic findings that mimic lung cancers. Distinguishing these infectious lesions from lung cancer remains challenging for radiologists and clinicians. In such cases, radiographic findings and clinical manifestations can be highly suggestive of lung cancer, and misdiagnosis can significantly delay the initiation of appropriate treatment. Likewise, the findings of imaging studies cannot replace the detection of a species as the aetiological agent. A biopsy is usually required to diagnose the infectious nature of the lesions. In this article, we review the clinical, histologic and radiologic features of the most common fungal infections that can mimic primary lung cancers, including paracoccidioidomycosis, histoplasmosis, cryptococcosis, coccidioidomycosis, aspergillosis, mucormycosis and blastomycosis.