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Focus on invasive mucormycosis in paediatric haematology oncology patients: a series of 11 cases
Author(s) -
PhulpinWeibel Aurélie,
Rivier Alexandre,
Leblanc Thierry,
Bertrand Yves,
Chastagner Pascal
Publication year - 2013
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1111/myc.12010
Subject(s) - mucormycosis , medicine , hematology , retrospective cohort study , antifungal , surgery , intensive care medicine , dermatology
Summary Mucormycosis has emerged as an increasingly important infection in oncology centres with high mortality, especially in severely immunocompromised patients. We carried out a retrospective study of 11 children with mucormycosis treated in seven French oncology‐haematology paediatric wards during the period from 1991 to 2011. Lichtheimia corymbifera and Mucor spp. were the predominant pathogens. Treatment regimens included antifungal therapy, reversal of underlying predisposing risk factors and surgical debridement. Although mucormycosis is associated with high mortality, this infection could be cured in eight of our cases of severely immunocompromised paediatric cancer patients.