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New repellent effective against African malaria mosquito Anopheles gambiae : implications for vector control
Author(s) -
HODSON C. N.,
YU Y.,
PLETTNER E.,
ROITBERG B. D.
Publication year - 2016
Publication title -
medical and veterinary entomology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 82
eISSN - 1365-2915
pISSN - 0269-283X
DOI - 10.1111/mve.12188
Subject(s) - anopheles gambiae , biology , malaria , vector (molecular biology) , anopheles , mosquito control , host (biology) , plasmodium (life cycle) , bed nets , toxicology , zoology , ecology , parasite hosting , immunology , biochemistry , world wide web , computer science , gene , recombinant dna
Abstract Anopheles gambiae Giles sensu stricto (Diptera: Culicidae) is a vector for Plasmodium , the causative agent of malaria. Current control strategies to reduce the impact of malaria focus on reducing the frequency of mosquito attacks on humans, thereby decreasing Plasmodium transmission. A need for new repellents effective against Anopheles mosquitoes has arisen because of changes in vector behaviour as a result of control strategies and concern over the health impacts of current repellents. The response of A. gambiae to potential repellents was investigated through an electroantennogram screen and the most promising of these candidates (1‐allyloxy‐4‐propoxybenzene, 3c { 3,6 }) chosen for behavioural testing. An assay to evaluate the blood‐host seeking behaviour of A. gambiae towards a simulated host protected with this repellent was then performed. The compound 3c { 3,6 } was shown to be an effective repellent, causing mosquitoes to reduce their contact with a simulated blood‐host and probe less at the host odour. Thus, 3c { 3,6 } may be an effective repellent for the control of A. gambiae .