Open AccessRecognition of lettuce downy mildew effector BLR38 in Lactuca serriola LS102 requires two unlinked loci
Author(s) -
Pelgrom Alexandra J. E.,
Eikelhof Jelle,
Elberse Joyce,
Meisrimler ClaudiaNicole,
Raedts Rob,
Klein Joël,
Van den Ackerveken Guido
Publication year - 2019
Publication title -
molecular plant pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 103
eISSN - 1364-3703
pISSN - 1464-6722
DOI - 10.1111/mpp.12751
Subject(s) - downy mildew , effector , biology , lactuca , oomycete , gene , genetics , plant disease resistance , botany , microbiology and biotechnology
Summary Plant‐pathogenic oomycetes secrete effector proteins to suppress host immune responses. Resistance proteins may recognize effectors and activate immunity, which is often associated with a hypersensitive response (HR). Transient expression of effectors in plant germplasm and screening for HR has proven to be a powerful tool in the identification of new resistance genes. In this study, 14 effectors from the lettuce downy mildew Bremia lactucae race Bl:24 were screened for HR induction in over 150 lettuce accessions. Three effectors—BLN06, BLR38 and BLR40—were recognized in specific lettuce lines. The recognition of effector BLR38 in Lactuca serriola LS102 did not co‐segregate with resistance against race Bl:24, but was linked to resistance against multiple other B. lactucae races. Two unlinked loci are both required for effector recognition and are located near known major resistance clusters. Gene dosage affects the intensity of the BLR38‐triggered HR, but is of minor importance for disease resistance.