Open AccessExtracellular ATP : a potential regulator of plant cell death
Author(s) -
Feng Hanqing,
Guan Dongdong,
Bai Jingyue,
Sun Kun,
Jia Lingyun
Publication year - 2015
Publication title -
molecular plant pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 103
eISSN - 1364-3703
pISSN - 1464-6722
DOI - 10.1111/mpp.12219
Subject(s) - extracellular , adenosine triphosphate , biology , intracellular , microbiology and biotechnology , regulator , signalling , programmed cell death , biochemistry , gene , apoptosis
Summary Adenosine 5′‐triphosphate ( ATP ) has been regarded as an intracellular energy currency molecule for many years. In recent decades, it has been determined that ATP is released into the extracellular milieu by animal, plant and microbial cells. In animal cells, this extracellular ATP ( eATP ) functions as a signalling compound to mediate many cellular processes through its interaction with membrane‐associated receptor proteins. It has also been reported that eATP is a signalling molecule required for the regulation of plant growth, development and responses to environmental stimuli. Recently, the first plant receptor for eATP was identified in A rabidopsis thaliana . Interestingly, some studies have shown that eATP is of particular importance in the control of plant cell death. In this review article, we summarize and discuss the theoretical and experimental advances that have been made with regard to the roles and mechanisms of eATP in plant cell death. We also make an attempt to address some speculative aspects to help develop and expand future research in this area.