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Streptomyces coelicolor produces actinorhodin, a blue‐pigmented, redox‐active secondary metabolite that has potent antibacterial activity. Mutations in the Staphylococcus aureus walRKHI operon confer low‐level resistance to actinorhodin, suggestive of cell enveloperelated effects. For details, see the article by Mak and Nodwell on pp. 597–613 of this issue.
Publication year - 2017
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13521
Subject(s) - actinorhodin , streptomyces coelicolor , operon , biology , staphylococcus aureus , microbiology and biotechnology , metabolite , secondary metabolite , genetics , streptomyces , escherichia coli , bacteria , gene , biochemistry