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Pseudomonas aeruginosa mutants lacking the gamma‐glutamylpolyamine synthetase PauA2 are inhibited for growth by spermine. Mutations in phoU suppress spermine toxicity and lead to pyocyanin overproduction. The spent medium (top row) of strains carrying a phoU mutation (three strains on right) displays a greenish‐blue coloration indicative of pyocyanin, as confirmed by its characteristic color after extraction with chloroform (middle row) and with acid (bottom row). For details, see the article by Peng et al . on pp. 1037–1051 of this issue.
Publication year - 2017
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13511
Subject(s) - pyocyanin , biology , pseudomonas aeruginosa , mutant , spermine , mutation , microbiology and biotechnology , overproduction , biochemistry , bacteria , genetics , enzyme , biofilm , quorum sensing , gene