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Mrp family proteins are ATPases with a variety of functions. Bacillus subtilis protein‐tyrosine kinase PtkA phosphorylates the Mrp protein SalA. Phosphorylated SalA represses scoC which encodes a repressor of aprE , encoding a major exoprotease. SalA and PtkA contain the same ATP‐binding Walker domain, and have thus presumably arose from a common ancestor. For details, see the article by Derouiche et al . on pp. 1195–1208 of this issue.
Publication year - 2015
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13199
Subject(s) - biology , bacillus subtilis , phosphorylation , genetics , bacteria