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Helicobacter pyloricolonizes the human stomach where it secretes a pore‐forming toxin known as vacuolating cytotoxin A (VacA). Using a combination of biochemistry and negative stain electron microscopy, Pyburn et al . show that the monomeric VacA oligomerizes into membrane‐inserted hexamers. For details, see the article by Pyburn et al . on pp. 22–36 of this issue.
Publication year - 2016
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13193
Subject(s) - biology , negative stain , stain , helicobacter pylori , toxin , microbial toxins , electron microscope , microbiology and biotechnology , staining , genetics , physics , optics
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