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Unsaturated fatty acids (UFA) can inhibit bacterial conjugation, which is powered by a set of ATPases that energize plasmid relaxation and unwinding, DNA transfer, pilus biogenesis and transport. In the conjugative plasmid R388, UFA function as non‐competitive inhibitors of the TwrD ATPase that participates in pilus biogenesis. For details, see the article by Ripoll‐Rozada et al . on pp. 912–921 of this issue.
Publication year - 2016
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13185
Subject(s) - plasmid , biology , biogenesis , pilus , bacterial conjugation , dna , atpase , biochemistry , gene , escherichia coli , enzyme