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Mycobacterium tuberculosis (green) uses a surface‐exposed sphingomyelinase (ribbon diagram) to cleave the eukaryotic membrane lipid sphingomyelin (space filling model). This activity lyses erythrocytes and enhances replication of Mtb in macrophages (red/blue). For details, see the article by Speer et al. on pp. 881–897 of this issue.
Publication year - 2015
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13163
Subject(s) - sphingomyelin , biology , cleave , mycobacterium tuberculosis , microbiology and biotechnology , membrane , tuberculosis , genetics , dna , medicine , pathology
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