Premium
BamA proteins are required for the folding and insertion of β‐barrel containing integral outer membrane proteins (OMPs). Despite their wide conservation, BamA orthologs function in a speciesspecific manner. Genetic studies of hybrid BamA proteins demonstrates that defects in hybrids containing orthologous POTRA domains can be rescued by compensatory mutations within the β‐barrel domain (highlighted residues). For details, see the article by Browning et al . on pp. 646–659 of this issue.
Publication year - 2015
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13148
Subject(s) - bama , biology , barrel (horology) , folding (dsp implementation) , integral membrane protein , function (biology) , computational biology , protein folding , genetics , phenotype , membrane protein , bacterial outer membrane , gene , microbiology and biotechnology , membrane , escherichia coli , engineering , mechanical engineering , electrical engineering