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Rhomboid proteases in invasion and replication of Apicomplexa
Author(s) -
Stewart Rebecca J.,
Tonkin Christopher J.
Publication year - 2015
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.13032
Subject(s) - biology , rhomboid , apicomplexa , proteases , replication (statistics) , evolutionary biology , genetics , computational biology , microbiology and biotechnology , virology , immunology , enzyme , biochemistry , malaria , plasmodium falciparum
Summary In this issue of M olecular M icrobiology , Rugarabamu and colleagues investigate the role of rhomboid proteases responsible for adhesin shedding during invasion of the apicomplexan parasite T oxoplasma gondii . This study, together with several other recent publications, raises new questions about the function of these rhomboids in T oxoplasma , while also strongly arguing against other recently proposed roles for these proteases.
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