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Are you talking to me? A possible role for γ‐butyrolactones in interspecies signalling
Author(s) -
Nodwell Justin R.
Publication year - 2014
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.12787
Subject(s) - biology , signalling , secondary metabolism , regulator , extracellular , microbiology and biotechnology , streptomyces coelicolor , bacteria , metabolism , biosynthesis , cell signaling , biochemistry , signal transduction , genetics , enzyme , gene , streptomyces
Summary The secreted γ‐butyrolactone signalling molecule SVB1 regulates the biosynthesis of jadomycin in S treptomyces venezuelae . Interestingly, this molecule is identical to SCB3 , a secreted regulator of secondary metabolism in S treptomyces coelicolor . This is a departure for this class of signalling molecules as there are no previous reports of identical signalling molecules produced in different species. One implication of this work is that different species of bacteria could use shared extracellular signals to co‐ordinate secondary metabolism when and if it is advantageous to do so.