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Pseudomonas putida S16 mineralizes nicotine, an environmental toxicant, to carbon dioxide and water. Degradation of nicotine relies on enzymes in the pyrrolidine pathway that are regulated by the NicR2 repressor, a member of the TetR family of regulatory proteins. For further details of the NicR2‐mediated regulatory mechanism, readers are referred to the article by Xu et al. on pp. 1252‐1269 of this issue.
Publication year - 2014
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1111/mmi.12563
Subject(s) - pseudomonas putida , repressor , pyrrolidine , biology , nicotine , enzyme , toxicant , tetr , computational biology , biochemistry , stereochemistry , gene , chemistry , gene expression , toxicity , organic chemistry , neuroscience