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Between‐day reliability of local thermal hyperemia in the forearm and index finger using single‐point laser Doppler flowmetry
Author(s) -
McGarr Gregory W.,
Hodges Gary J.,
Cheung Stephen S.
Publication year - 2017
Publication title -
microcirculation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.793
H-Index - 83
eISSN - 1549-8719
pISSN - 1073-9688
DOI - 10.1111/micc.12395
Subject(s) - forearm , laser doppler velocimetry , reliability (semiconductor) , medicine , plateau (mathematics) , nuclear medicine , surgery , blood flow , biomedical engineering , mathematics , cardiology , physics , mathematical analysis , power (physics) , quantum mechanics
Abstract Objective To assess between‐day reliability for LTH in glabrous and nonglabrous index finger skin and nonglabrous forearm skin, with single‐point laser Doppler flowmetry. Methods Part‐1: In healthy, habitually active males (n=10), LTH was examined twice (~7‐10 days apart) for both skin types on the index finger. Part‐2: Identical testing was performed on the volar forearm. Local heating (33‐42°C at 1°C·20 s −1 + 20 minutes at 44°C) was performed at all skin sites and baseline, initial peak, and plateau phases were identified. Data were expressed as raw CVC (laser‐Doppler flux/MAP), and as CVC normalized to baseline (% CVC 33°C ) and maximum heating (% CVC 44°C ). Reliability was assessed using between‐day mean difference, % CV , and ICC. Results Reliability (% CV ) was poor at baseline for all forms of data presentation and for other phases with % CVC 33°C . At the initial peak and plateau, reliability was moderate‐poor (20%‐26%) for CVC and good‐moderate (6%‐18%) for % CVC 44°C . Reliability was good‐moderate for vasodilatory onset time (10%‐23%) and time to initial peak (6%‐13%). Conclusions For all sites, LTH reliability was acceptable for the timing, and for the initial peak and plateau using CVC or % CVC 44°C .