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Mobile genetic elements: in silico , in vitro , in vivo
Author(s) -
Arkhipova Irina R.,
Rice Phoebe A.
Publication year - 2016
Publication title -
molecular ecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.619
H-Index - 225
eISSN - 1365-294X
pISSN - 0962-1083
DOI - 10.1111/mec.13543
Subject(s) - in silico , mobile genetic elements , biology , transposable element , computational biology , genome , function (biology) , genetics , evolutionary biology , gene
Mobile genetic elements ( MGE s), also called transposable elements ( TE s), represent universal components of most genomes and are intimately involved in nearly all aspects of genome organization, function and evolution. However, there is currently a gap between the fast pace of TE discovery in silico , driven by the exponential growth of comparative genomic studies, and a limited number of experimental models amenable to more traditional in vitro and in vivo studies of structural, mechanistic and regulatory properties of diverse MGE s. Experimental and computational scientists came together to bridge this gap at a recent conference, ‘Mobile Genetic Elements: in silico , in vitro , in vivo’ , held at the Marine Biological Laboratory ( MBL ) in Woods Hole, MA , USA .