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Mitochondrial genomes of domestic animals need scrutiny
Author(s) -
Shi NiNi,
Fan Long,
Yao YongGang,
Peng MinSheng,
Zhang YaPing
Publication year - 2014
Publication title -
molecular ecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.619
H-Index - 225
eISSN - 1365-294X
pISSN - 0962-1083
DOI - 10.1111/mec.12955
Subject(s) - biology , mitochondrial dna , genbank , haplogroup , phylogenetic tree , genome , genetics , dna sequencing , evolutionary biology , dna , human mitochondrial dna haplogroup , phylogenetics , gene , haplotype , allele
More than 1000 complete or near‐complete mitochondrial DNA (mt DNA ) sequences have been deposited in GenBank for eight common domestic animals (cattle, dog, goat, horse, pig, sheep, yak and chicken) and their close wild ancestors or relatives, as well. Nevertheless, few efforts have been performed to evaluate the sequence data quality. Herein, we conducted a phylogenetic survey of these complete or near‐complete mt DNA sequences based on mt DNA haplogroup trees for the eight animals. We show that errors due to artificial recombination, surplus of mutations and phantom mutations do exist in 14.5% (194/1342) of mt DNA sequences and all of them should be treated with wide caution. We propose some caveats for future mt DNA studies of domestic animals.