Open AccessEarly childhood growth and cognitive outcomes: Findings from the MAL‐ED study
Author(s) -
Scharf Rebecca J.,
Rogawski Elizabeth T.,
MurrayKolb Laura E.,
Maphula Angelina,
Svensen Erling,
Tofail Fahmida,
Rasheed Muneera,
Abreu Claudia,
Vasquez Angel Orbe,
Shrestha Rita,
Pendergast Laura,
Mduma Estomih,
Koshy Beena,
Conaway Mark R.,
PlattsMills James A.,
Guerrant Richard L.,
DeBoer Mark D.
Publication year - 2018
Publication title -
maternal and child nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 63
eISSN - 1740-8709
pISSN - 1740-8695
DOI - 10.1111/mcn.12584
Subject(s) - medicine , anthropometry , toddler , bayley scales of infant development , cognition , pediatrics , early childhood , child development , head circumference , demography , cognitive development , cognitive skill , gerontology , developmental psychology , birth weight , psychomotor learning , psychiatry , psychology , pregnancy , genetics , sociology , biology
Although many studies around the world hope to measure or improve developmental progress in children to promote community flourishing and productivity, growth is sometimes used as a surrogate because cognitive skills are more difficult to measure. Our objective was to assess how childhood measures of anthropometry correlate with measures of child development in low‐income settings with high prevalence of poor nutrition and enteric disease, to inform studies considering growth outcomes in the absence of direct child developmental skill assessment. Children from the MAL‐ED study were followed from birth to 24 months of age in field sites in 8 low‐ and middle‐income countries across 3 continents. Monthly weight, length, and head circumference measurements were performed. At 24 months, the Bayley Scales of Infant and Toddler Development was administered. We correlated cognitive measures at 24 months with anthropometric measurements from birth to 2 years comparing 3 constructs: absolute attained monthly measures, summative difference in measures from the mean growth curve, and rate of change in measures. Growth faltering at multiple time periods is related to Bayley cognitive outcomes at 24 months. Birthweight, overall growth by 18–24 months, and rate of growth in the 6‐ to 18‐month period were most associated with 24‐month developmental scores. In this study, head circumference measurements, compared with length, was more closely linked to cognitive scores at 24 months. Notably, all studies between growth and cognitive outcomes exhibited low r 2 values (0.001–0.049). Anthropometric measures, particularly head circumference, were related to cognitive development, although explaining a low percent of variance. When feasible, direct measures of child development may be more useful.